But just a day earlier, in a webinar led by Mark Blumenthal, the executive director of the American Botanical Council (ABC) on The Science of Herbal Medicines: What Works and Why ( see my last blogpost for a summary), I learned that ginkgo extract had been shown in a meta-analysis of several “gold-standard” clinical trials to be effective in improving cognitive function in people with mild dementia. An earlier examination of 16 clinical trials in 2005 also showed that gingko was just as effective in improving mental performance (. remembering shopping lists and short term memory) in non-impaired, healthy adults.
The most common immunosuppression regimen used in patients after liver transplant is the combination of calcineurin inhibitor, usually tacrolimus, with prednisone. Recurrence of AIH in the transplanted liver can occur in 25% to 30% of the cases and seems to be more common when prednisone is discontinued. 41,42 Thus prednisone is usually continued at low doses after transplant. Autoimmune hepatitis recurrence in the liver transplant can often be successfully treated by reintroducing prednisone and optimizing calcineurin inhibitors. A combination of prednisone and azathioprine has also been used to treat recurrent AIH. These patients have a similar prognosis as transplanted patients who do not have recurrent AIH. 41