The patient (male, age 85 years) seen in Figure 3 presented with a facial “rash.” Palpation and examination revealed erythema, dryness, scaling, and thickening of the skin on the forehead, nose, cheeks, and chin. KOH test for Demodex mites was negative; however, clinical appearance and symptoms strongly suggested the possibility of Demodex infestation. The patient was treated with topical crotamiton twice daily, instructed to use a moisturizer, and returned four weeks later for a follow-up visit. The patient showed marked improvement in the central third of the face and was instructed to continue crotamiton application twice daily. A second follow-up visit four weeks later showed marked reduction in erythema, with no evidence of erythema detected on the forehead, nose, cheeks, and chin. Crotamiton application was decreased to once daily at bedtime.